Zinc(II) Complexes of Schiff Bases Derived from Bis-(2-hydrazino-1,3,4-thiadiazole-5-yl)Arene/ Alkanes: Synthesis, Spectral Characterization and Biological Properties

A novel series of zinc(II) complexes of type [ZnL(H₂O)₂], has been synthesized by the reaction of zinc(II) acetate dihydrate with Schiff bases (H2L) derived from bis-(2-hydrazino-1,3,4-thiadiazole-5-yl)arene/alkanes and 2-hydroxynaphthaldehyde/3,5-dichlorosalicyldehyde in presence of a base. The structures of all the zinc complexes were proposed by elemental analysis and spectroscopic data (IR, ¹H, ¹³C NMR). TGA investigations were carried out to confirm the presence of coordinated water molecules in the zinc complexes. The powder crystal structure of one particular zinc complex has been analyzed by XRD diffraction method and SEM studies have been carried out to investigate the surface morphology. The biological studies reveal that the synthesized zinc complexes possess good antimicrobial properties against different species of pathogenic fungi and bacteria.