Writer's Cramp

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

Writer's cramp (WC) is the most common focal hand dystonia. It is characterized by abnormal, involuntary movements of the hand that occur mainly or exclusively with writing, with overflow to muscles that are not normally involved in this task. Although often regarded as a sporadic disorder that occurs in the setting of frequent writing, an underlying genetic predisposition has been demonstrated in some patients. The pathophysiology of WC is complex, and appears to involve motor and sensory systems as well as sensorimotor integration. Knowledge of the underlying pathophysiology of WC has been helpful in designing novel therapeutic approaches. .

Original languageEnglish
Title of host publicationEncyclopedia of Neuroscience
PublisherElsevier Ltd.
Pages533-537
Number of pages5
ISBN (Print)9780080450469
DOIs
StatePublished - 2009
Externally publishedYes

Keywords

  • Anticholinergic
  • Basal ganglia
  • Botulinum toxin
  • Co-contraction
  • Deep brain stimulation
  • Dopa-responsive dystonia
  • Dystonia
  • Endophenotype
  • Focal dystonia
  • Graphospasm
  • Overflow
  • Sensorimotor integration
  • Sensory trick
  • Task-specific dystonia
  • Writer's cramp
  • γ-Aminobutyric acid

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