Wnt/PCP Instructions for Cilia in Left-Right Asymmetry

Jun Wu; Marek Mlodzik

doi:10.1016/j.devcel.2017.02.023

Wnt/PCP Instructions for Cilia in Left-Right Asymmetry

Jun Wu, Marek Mlodzik

Research output: Contribution to journal › Short survey › peer-review

10 Scopus citations

Abstract

Wnt-Frizzled/planar cell polarity (PCP) signaling establishes cell orientation within the epithelial plane, but whether Wnts are instructive or permissive is debated. Reporting in Developmental Cell, Minegishi et al. (2017) uncover an instructive link from Wnt5a/b gradients to PCP-factor-regulated polarized cilia positioning that is essential to mouse embryo left-right asymmetry establishment.

Original language	English
Pages (from-to)	423-424
Number of pages	2
Journal	Developmental Cell
Volume	40
Issue number	5
DOIs	https://doi.org/10.1016/j.devcel.2017.02.023
State	Published - 13 Mar 2017

Access to Document

10.1016/j.devcel.2017.02.023

Cite this

@article{1ea3445522b94718aae94cb9183c1257,

title = "Wnt/PCP Instructions for Cilia in Left-Right Asymmetry",

abstract = "Wnt-Frizzled/planar cell polarity (PCP) signaling establishes cell orientation within the epithelial plane, but whether Wnts are instructive or permissive is debated. Reporting in Developmental Cell, Minegishi et al. (2017) uncover an instructive link from Wnt5a/b gradients to PCP-factor-regulated polarized cilia positioning that is essential to mouse embryo left-right asymmetry establishment.",

author = "Jun Wu and Marek Mlodzik",

note = "Publisher Copyright: {\textcopyright} 2017",

year = "2017",

month = mar,

day = "13",

doi = "10.1016/j.devcel.2017.02.023",

language = "English",

volume = "40",

pages = "423--424",

journal = "Developmental Cell",

issn = "1534-5807",

publisher = "Cell Press",

number = "5",

}

TY - JOUR

T1 - Wnt/PCP Instructions for Cilia in Left-Right Asymmetry

AU - Wu, Jun

AU - Mlodzik, Marek

PY - 2017/3/13

Y1 - 2017/3/13

N2 - Wnt-Frizzled/planar cell polarity (PCP) signaling establishes cell orientation within the epithelial plane, but whether Wnts are instructive or permissive is debated. Reporting in Developmental Cell, Minegishi et al. (2017) uncover an instructive link from Wnt5a/b gradients to PCP-factor-regulated polarized cilia positioning that is essential to mouse embryo left-right asymmetry establishment.

AB - Wnt-Frizzled/planar cell polarity (PCP) signaling establishes cell orientation within the epithelial plane, but whether Wnts are instructive or permissive is debated. Reporting in Developmental Cell, Minegishi et al. (2017) uncover an instructive link from Wnt5a/b gradients to PCP-factor-regulated polarized cilia positioning that is essential to mouse embryo left-right asymmetry establishment.

UR - http://www.scopus.com/inward/record.url?scp=85014994398&partnerID=8YFLogxK

U2 - 10.1016/j.devcel.2017.02.023

DO - 10.1016/j.devcel.2017.02.023

M3 - Short survey

C2 - 28292419

AN - SCOPUS:85014994398

SN - 1534-5807

VL - 40

SP - 423

EP - 424

JO - Developmental Cell

JF - Developmental Cell

IS - 5

ER -

Wnt/PCP Instructions for Cilia in Left-Right Asymmetry

Abstract

Access to Document

Fingerprint

Cite this