Wilson's disease and the neuroleptic malignant syndrome

Peter Buckley, Eamonn Carmody, Michael Hutchinson

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Wilson's Disease (Hepatolenticular degeneration) is an uncommon disorder of copper metabolism, characterised by excessive copper deposition in the liver, brain and eyes. Psychiatric symptoms were prominent in eight of the twelve patients originally described by Wilson some 88 years ago1. Since then a wide range of psychiatric presentations have been documented including behavioural disturbances, affective psychoses, schizophrenia-like psychoses, intellectual deterioration and dementia.2'3 Here we describe a patient who presented with a psychiatric disturbance, was treated with neuroleptic medication and subsequently developed Neuroleptic Malignant Syndrome (NMS).

Original languageEnglish
Pages (from-to)138-139
Number of pages2
JournalIrish Journal of Psychological Medicine
Issue number2
StatePublished - Sep 1990
Externally publishedYes


  • Hepatolenticular degeneration
  • Neuroleptic Malignant Syndrome


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