Why an Alternative to Blood Transfusion?

Aryeh Shander, Lawrence Tim Goodnough

Research output: Contribution to journalReview articlepeer-review

48 Scopus citations


Allogeneic blood transfusions have been associated with several risks and complications and with worse outcomes in a substantial number of patient populations and clinical scenarios. Allogeneic blood is costly and difficult to procure, transport, and store. Global and local shortages are imminent. Alternatives to transfusion provide many advantages, and their use is likely to improve outcomes as safer and more effective agents are developed.

Original languageEnglish
Pages (from-to)261-277
Number of pages17
JournalCritical Care Clinics
Issue number2
StatePublished - Apr 2009


  • Allogeneic
  • Complication
  • Cost
  • Outcome
  • Risk
  • Transfusion


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