TY - JOUR
T1 - What atherosclerosis findings can CT see in sudden coronary death
T2 - Plaque rupture versus plaque erosion
AU - van den Hoogen, Inge J.
AU - Gianni, Umberto
AU - Al Hussein Alawamlh, Omar
AU - Wijeratne, Rashmi
AU - Jinnouchi, Hiroyuki
AU - Finn, Aloke
AU - Earls, James P.
AU - Virmani, Renu
AU - Lin, Fay Y.
N1 - Funding Information:
The research in this article was supported in part by GE healthcare , and by a generous gift from the Dalio Institute of Cardiovascular Imaging (New York, NY) and the Michael Wolk Foundation (New York, NY) .
Funding Information:
The research in this article was supported in part by GE healthcare, and by a generous gift from the Dalio Institute of Cardiovascular Imaging (New York, NY) and the Michael Wolk Foundation (New York, NY).
Publisher Copyright:
© 2020
PY - 2020/5/1
Y1 - 2020/5/1
N2 - Sudden death is the most abrupt clinical presentation of acute coronary syndrome. The presence of acute luminal thrombosis is the histopathological hallmark of sudden coronary death. There are 3 main etiologies that can give rise to an acute luminal thrombus: plaque rupture, plaque erosion and, less frequently, eruptive calcified nodules. Coronary computed tomography angiography (CCTA) has the ability to identify high-risk plaque features of coronary artery disease that are associated with future adverse cardiac events. In this report, we illustrate 2 cases of suspected sudden coronary death with a thorough description of how CCTA can be employed to detect high-risk plaque features using histopathology as a gold standard.
AB - Sudden death is the most abrupt clinical presentation of acute coronary syndrome. The presence of acute luminal thrombosis is the histopathological hallmark of sudden coronary death. There are 3 main etiologies that can give rise to an acute luminal thrombus: plaque rupture, plaque erosion and, less frequently, eruptive calcified nodules. Coronary computed tomography angiography (CCTA) has the ability to identify high-risk plaque features of coronary artery disease that are associated with future adverse cardiac events. In this report, we illustrate 2 cases of suspected sudden coronary death with a thorough description of how CCTA can be employed to detect high-risk plaque features using histopathology as a gold standard.
UR - http://www.scopus.com/inward/record.url?scp=85076237196&partnerID=8YFLogxK
U2 - 10.1016/j.jcct.2019.07.005
DO - 10.1016/j.jcct.2019.07.005
M3 - Review article
C2 - 31813783
AN - SCOPUS:85076237196
VL - 14
SP - 214
EP - 218
JO - Journal of Cardiovascular Computed Tomography
JF - Journal of Cardiovascular Computed Tomography
SN - 1934-5925
IS - 3
ER -