Water immersion-induced skin wrinkling is related to heart rate variability

Sithu Win; Louis Salciccioli; Haroon Kamran; Paramdeep Baweja; Mark Stewart; Jason M. Lazar

doi:10.1159/000316043

Water immersion-induced skin wrinkling is related to heart rate variability

Sithu Win, Louis Salciccioli, Haroon Kamran, Paramdeep Baweja, Mark Stewart, Jason M. Lazar

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

Water immersion-induced skin wrinkling (WISW) is dependent on intact peripheral sympathetic function. WISW was hypothesized to reflect autonomic function in subjects without peripheral neuropathy. We prospectively studied 70 healthy subjects (aged 31 ± 8 years, 63% females) without cardiovascular risk factors or neurological disease. All subjects underwent short-term heart rate variability (HRV) studies. Time and frequency domain variables were derived including the HRV index. WISW was graded using a previously validated scale of 1-4 of which 18.6% of subjects exhibited grade 1 (minimal) WISW and 35.7% had grade 2 WISW. On multivariate analysis using the HRV index, WISW was independently related to height and the HRV index. We conclude that WISW is related to central autonomic function.

Original language	English
Pages (from-to)	247-250
Number of pages	4
Journal	Cardiology
Volume	116
Issue number	4
DOIs	https://doi.org/10.1159/000316043
State	Published - Oct 2010
Externally published	Yes

Keywords

Autonomic function
Heart rate variability
Water-induced skin wrinkling

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10.1159/000316043

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title = "Water immersion-induced skin wrinkling is related to heart rate variability",

abstract = "Water immersion-induced skin wrinkling (WISW) is dependent on intact peripheral sympathetic function. WISW was hypothesized to reflect autonomic function in subjects without peripheral neuropathy. We prospectively studied 70 healthy subjects (aged 31 ± 8 years, 63% females) without cardiovascular risk factors or neurological disease. All subjects underwent short-term heart rate variability (HRV) studies. Time and frequency domain variables were derived including the HRV index. WISW was graded using a previously validated scale of 1-4 of which 18.6% of subjects exhibited grade 1 (minimal) WISW and 35.7% had grade 2 WISW. On multivariate analysis using the HRV index, WISW was independently related to height and the HRV index. We conclude that WISW is related to central autonomic function.",

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AU - Win, Sithu

AU - Salciccioli, Louis

AU - Kamran, Haroon

AU - Baweja, Paramdeep

AU - Stewart, Mark

AU - Lazar, Jason M.

PY - 2010/10

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Water immersion-induced skin wrinkling is related to heart rate variability

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Keywords

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