Vulnerable Plaque: Definition, Diagnosis, and Treatment

Pedro R. Moreno

Research output: Contribution to journalReview articlepeer-review

78 Scopus citations


This article provides a systematic approach to vulnerable plaques. It is divided into 4 sections. The first section is devoted to definition, incidence, anatomic distribution, and clinical presentation. The second section is devoted to plaque composition, setting up the foundations to understand plaque vulnerability. The third section relates to invasive plaque imaging. The fourth section is devoted to therapy, from conservative pharmacologic options to aggressive percutaneous coronary intervention alternatives.

Original languageEnglish
Pages (from-to)1-30
Number of pages30
JournalCardiology Clinics
Issue number1
StatePublished - Feb 2010
Externally publishedYes


  • Atherosclerosis
  • Neovascularization
  • Plaque
  • Rupture
  • Thrombosis
  • Vulnerable


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