Visual compatibility of enalaprilat with commonly used critical care medications during simulated Y-site injection

N. A. Halpern, R. D. Colucci, M. Alicea, R. Greenstein

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Physical incompatibility studies between an intravenous angiotensin-converting enzyme inhibitor, enalaprilat, and potentially coadministrable ICU medications have been performed. Forty-one medications and four solutions were evaluated. The medications were anesthetic/narcotics, antibiotics, an anticoagulant, a bronchodilator, electrolyte solutions, fluids, H-2 receptor blocking agents, steroids and vasoactive agents. There was no turbidity, precipitation, or color change caused by the admixing of enalaprilat with any of the 45 agents studied. This study did not take bioavailability into consideration.

Original languageEnglish
Pages (from-to)294-297
Number of pages4
JournalInternational Journal of Clinical Pharmacology Therapy and Toxicology
Volume27
Issue number6
StatePublished - 1989
Externally publishedYes

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