Visit-to-Visit variability of blood pressure and renal function decline in patients with diabetic chronic kidney disease

Kei Yokota, Masamichi Fukuda, Yoshio Matsui, Kazuomi Kario, Kenjiro Kimura

Research output: Contribution to journalArticlepeer-review

20 Scopus citations

Abstract

The authors previously reported that the visit-to-visit variability of blood pressure is correlated with renal function decline in nondiabetic chronic kidney disease. Little is known about the association between visit-to-visit variability and renal function decline in patients with diabetic chronic kidney disease. The authors retrospectively studied 69 patients with diabetic chronic kidney disease stage 3a, 3b, or 4. The standard deviation and coefficient of variation of blood pressure in 12 consecutive visits were defined as visit-to-visit variability of blood pressure. The median observation period was 32 months. In univariate correlation, the standard deviation and coefficient of variation of blood pressure were not significantly associated with the slope of estimated glomerular filtration rate. There was no significant association between the visit-to-visit variability of blood pressure and renal function decline in patients with diabetic chronic kidney disease, in contrast with our previous study of nondiabetic patients with chronic kidney disease.

Original languageEnglish
Pages (from-to)362-366
Number of pages5
JournalJournal of Clinical Hypertension
Volume16
Issue number5
DOIs
StatePublished - May 2014
Externally publishedYes

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