TY - JOUR
T1 - Virilizing adrenocortical adenoma studied by selective adrenal venography
AU - Gabrilove, J. L.
AU - Nicolis, G. L.
AU - Mitty, H. A.
PY - 1976/5/15
Y1 - 1976/5/15
N2 - A 15-year-old girl with primary amenorrhea, hirsutism, and enlargement of the clitoris was found to have an increased titer of the urinary neutral 17-ketosteroids which failed to decrease after the administration of dexamethasone and an adrenal tumor was demonstrable on venography. Analysis of the adrenal venous effluent revealed gradients on the side of the tumor for testosterone, androstenedione, estradiol, and dehydroepiandrosterone sulfate. Following removal of the tumor, the hirsutism improved markedly, the menses returned, and sexual maturation progressed.
AB - A 15-year-old girl with primary amenorrhea, hirsutism, and enlargement of the clitoris was found to have an increased titer of the urinary neutral 17-ketosteroids which failed to decrease after the administration of dexamethasone and an adrenal tumor was demonstrable on venography. Analysis of the adrenal venous effluent revealed gradients on the side of the tumor for testosterone, androstenedione, estradiol, and dehydroepiandrosterone sulfate. Following removal of the tumor, the hirsutism improved markedly, the menses returned, and sexual maturation progressed.
UR - http://www.scopus.com/inward/record.url?scp=0017084178&partnerID=8YFLogxK
U2 - 10.1016/0002-9378(76)90589-5
DO - 10.1016/0002-9378(76)90589-5
M3 - Article
C2 - 178182
AN - SCOPUS:0017084178
SN - 0002-9378
VL - 125
SP - 180
EP - 184
JO - American Journal of Obstetrics and Gynecology
JF - American Journal of Obstetrics and Gynecology
IS - 2
ER -