Vesicoureteral reflux in kidney transplantation

Nina M. Molenaar, Robert C. Minnee, Frederike J. Bemelman, Mirza M. Idu

Research output: Contribution to journalArticlepeer-review

19 Scopus citations

Abstract

Background: Vesicoureteral reflux (VUR) is frequently found after transplantation, but its impact on graft function, urine tract infection, and graft loss remains uncertain. Therefore our objective was to evaluate the effects of VUR on the outcome of renal transplantation. Material and Methods: We included 1008 adult renal transplant recipients of whom a 1-week posttransplant voiding cystourethrogram was available. Study end points included occurrence of bacteriuria, renal function, and graft survival. Results: In total, 106 (10.5%) of 1008 graft recipients had a diagnosis of VUR on voiding cystography. The incidence of bacteriuria was comparable in the reflux and nonreflux group (17% vs 17.4%, P = .91). There was no significant difference in renal function at 3 months and 1 year in patients with and without VUR. One- and 5-year graft survival in patients with VUR was 85.8% and 82.1% compared to 87.3% and 83.0% in patients without VUR (P = .68 and P = .80). Conclusion: Posttransplant VUR has no correlations with early bacteriuria, renal function, and graft survival.

Original languageEnglish
Pages (from-to)196-199
Number of pages4
JournalProgress in Transplantation
Volume27
Issue number2
DOIs
StatePublished - Jun 2017
Externally publishedYes

Keywords

  • Kidney transplantation
  • Urological complications
  • Vesicoureteral reflux

Fingerprint

Dive into the research topics of 'Vesicoureteral reflux in kidney transplantation'. Together they form a unique fingerprint.

Cite this