Vertebral artery injection of ouabain does not hasten arrhythmogenesis

Kujime Kenichi Kujime, Benjamin H. Natelson

Research output: Contribution to journalArticlepeer-review

6 Scopus citations

Abstract

Cats were infused with ouabain into either their vertebral artery or their femoral vein, and latencies to early and late ventricular arrhythmia and death were determined. No significant differences were found between the 2 groups. These data question the likelihood that the area postrema is, as has been recently proposed, the primary site of action for digitalis-induced cardiac arrhythmias.

Original languageEnglish
Pages (from-to)151-154
Number of pages4
JournalEuropean Journal of Pharmacology
Volume79
Issue number1-2
DOIs
StatePublished - 8 Apr 1982
Externally publishedYes

Keywords

  • Digitalis toxicity
  • Guinea pigs
  • Hindbrain
  • Vertebral artery

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