Ventricular-brain ratio and life course of illness in patients with affective disorder

Peter P. Roy-Byrne, Robert M. Post, Charles H. Kellner, Russell T. Joffe, Thomas W. Uhde

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The relationship between ventricular-brain ratio (VBR) on computed tomography of the brain and life course of illness was assessed in 59 hospitalized patients with recurrent affective disorder. In contrast to the implications of some, but not all, prior studies, VBR was not positively related to episode frequency, severity, pattern, or chronicity. In fact, when analyzed by sex, in both males and females, VBR was inversely related to several measures of illness chronicity.

Original languageEnglish
Pages (from-to)277-284
Number of pages8
JournalPsychiatry Research
Volume23
Issue number3
DOIs
StatePublished - Mar 1988
Externally publishedYes

Keywords

  • Ventricular-brain ratio (VBR)
  • computed tomography
  • life course of illness
  • recurrent affective disorder

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