Ventricular assist device in children with cardiac graft failure

Iki Adachi, Francisco A. Guzmán-Pruneda, Muhammad S. Khan, E. Dean McKenzie, Charles D. Fraser

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


We sought to determine whether ventricular assist device (VAD) support is an effective therapy in children with cardiac graft dysfunction. We conducted a retrospective review of VAD usage in this scenario at our institution. Although shortterm VAD support was highly successful (89% [eight out of nine] were bridged to recovery), only 29% (2 out of 7) with long-term VAD survived to retransplant. Of note, three out of five mortalities with long-term VAD were related to sepsis (two fungal and one Gram-negative bacterial). Infectious risk imposed by ongoing immunosuppressive therapy limits the role of long-term VAD in this population.

Original languageEnglish
Pages (from-to)729-730
Number of pages2
JournalASAIO Journal
Issue number6
StatePublished - 3 Nov 2015
Externally publishedYes


  • Cardiac graft failure
  • Children
  • Mechanical circulatory support
  • Pediatric
  • Ventricular assist device


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