Varying Approaches to Management of IgE-Mediated Food Allergy in Children Around the World

Melanie Lloyd, Paxton Loke, Douglas P. Mack, Scott H. Sicherer, Michael R. Perkin, Robert Boyle, Agnes Sze Yin Leung, Bee Wah Lee, Michael Levin, Katharina Blumchen, Alessandro Fiocchi, Motohiro Ebisawa, Lucila Camargo Lopes de Oliveira, Mimi L.K. Tang

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


Food allergy is a chronic disease that affects individuals of all ages and is a significant public health problem globally. This narrative overview examines clinical management strategies for IgE-mediated food allergy in children around the world to understand variations in practice. Information was drawn from clinical practice guidelines, recent research, the websites of professional and governmental bodies with expertise in food allergy, and clinical experts from a broad cross-section of geographical regions. The structure and delivery of clinical services, allergen avoidance and food labeling, and resources to support the management of allergic reactions in the community are discussed in detail. The adoption of emerging food immunotherapies is also explored. Wide variations in clinical management of food allergy were apparent across the different countries. Common themes were continuing issues with access to specialist care and recognition of the need to balance risk reduction with dietary and social restrictions to avoid unnecessary detrimental impacts on the quality of life of food allergy sufferers. Findings highlight the need for standardized presentation of practice and priorities, and may assist clinicians and researchers when engaging with government and funding agencies to address gaps.

Original languageEnglish
Pages (from-to)1010-1027.e6
JournalJournal of Allergy and Clinical Immunology: In Practice
Issue number4
StatePublished - Apr 2023


  • IgE-mediated food allergy
  • clinical variation
  • food allergy management
  • food immunotherapy
  • patient-centered care


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