Variants in LRRC7 lead to intellectual disability, autism, aggression and abnormal eating behaviors

Keyphrases

• Intellectual Disability 100%
• Aggression 100%
• Autism 100%
• PDZ Domain 100%
• Abnormal Eating Behavior 100%
• Leucine-rich Repeat Domain 66%
• Obesity 33%
• Leucine-rich Repeat 33%
• Gain-of-function mutation 33%
• Major Determinants 33%
• Co-immunoprecipitation (co-IP) 33%
• Protein Phosphatase 33%
• Signaling Molecules 33%
• Missense 33%
• Clinical Spectrum 33%
• Protein Family 33%
• Synaptic Targeting 33%
• Cytoskeletal Elements 33%
• HEK293 Cells 33%
• Interaction Partner 33%
• Ca2+/calmodulin-dependent Protein Kinase II 33%
• Neurodevelopmental Disorders 33%
• Histogenesis 33%
• Primary Neurons 33%
• Hyperphagia 33%
• In Vitro System 33%
• Synaptic Proteins 33%
• Glutamatergic Synapse 33%
• BioID 33%
• Animal Development 33%
• Intellectual Development 33%
• Tagged Protein 33%
• Two-hybrid 33%
• LRR Domain 33%
• Intellectual Behavior 33%

Neuroscience

• Leucine 100%
• PDZ Domain 100%
• Eating Behavior 100%
• Autism 100%
• Behavior (Neuroscience) 33%
• Attention Deficit Hyperactivity Disorder 33%
• In Vitro 33%
• Synapse 33%
• Phosphoprotein Phosphatase 1 33%
• Calcium Calmodulin Dependent Protein Kinase 33%
• Neurodevelopmental Disorder 33%
• Polyphagia 33%
• Protein Family 33%

Biochemistry, Genetics and Molecular Biology

• Leucine-Rich Repeat 100%
• Intellectual Disability 100%
• PDZ Domain 100%
• Synapse 33%
• Protein Family 33%
• Missense 33%
• Signaling Protein 33%
• Protein Phosphatase 1 33%
• Nerve Cell Culture 33%
• Glutamatergic 33%
• Histogenesis 33%
• Ca2+/Calmodulin-Dependent Protein Kinase II 33%
• Mental Development 33%
• LRR Domain 33%