Variant Creutzfeldt-Jakob disease: First two indigenous cases in Republic of Ireland. Case report and perspective

J. C. McHugh; D. Bradley; M. Hutchinson; F. Brett; J. Heffernan; R. Howley; M. Farrell; N. Tubridy

doi:10.1111/j.1468-1331.2007.01643.x

Variant Creutzfeldt-Jakob disease: First two indigenous cases in Republic of Ireland. Case report and perspective

J. C. McHugh, D. Bradley, M. Hutchinson, F. Brett, J. Heffernan, R. Howley, M. Farrell, N. Tubridy

Research output: Contribution to journal › Article › peer-review

Abstract

The first two cases of indigenous variant Creutzfeldt-Jakob disease (vCJD) in the Republic of Ireland are reported in two men, neither of whom had lived outside Ireland. Both diagnoses were made ante-mortem based on clinical presentation, brain imaging, positive 14-3-3 protein in one case, and tonsillar biopsy. We discuss some of the clinical aspects of vCJD and the significance of these cases in the Irish context.

Original language	English
Pages (from-to)	467-469
Number of pages	3
Journal	European Journal of Neurology
Volume	14
Issue number	4
DOIs	https://doi.org/10.1111/j.1468-1331.2007.01643.x
State	Published - Apr 2007
Externally published	Yes

Keywords

Ireland
Variant Creutzfeldt-Jakob disease

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10.1111/j.1468-1331.2007.01643.x

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abstract = "The first two cases of indigenous variant Creutzfeldt-Jakob disease (vCJD) in the Republic of Ireland are reported in two men, neither of whom had lived outside Ireland. Both diagnoses were made ante-mortem based on clinical presentation, brain imaging, positive 14-3-3 protein in one case, and tonsillar biopsy. We discuss some of the clinical aspects of vCJD and the significance of these cases in the Irish context.",

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AU - Bradley, D.

AU - Hutchinson, M.

AU - Brett, F.

AU - Heffernan, J.

AU - Howley, R.

AU - Farrell, M.

AU - Tubridy, N.

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Variant Creutzfeldt-Jakob disease: First two indigenous cases in Republic of Ireland. Case report and perspective

Abstract

Keywords

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