Vancomycin-resistant Enterococcus faecium meningitis successfully managed with linezolid: Case report and review of the literature

Cosmina Zeana; Christine J. Kubin; Phyllis Della-Latta; Scott M. Hammer

doi:10.1086/321896

Vancomycin-resistant Enterococcus faecium meningitis successfully managed with linezolid: Case report and review of the literature

Cosmina Zeana, Christine J. Kubin, Phyllis Della-Latta, Scott M. Hammer

Research output: Contribution to journal › Article › peer-review

127 Scopus citations

Abstract

Enterococci cause serious illness in immunocompromised patients and severely ill, hospitalized patients. Resistance to vancomycin has increased in frequency during the past few years. Limited therapeutic options are available for vancomycin-resistant enterococcal infections and the optimum therapy has not been established. We report a case of nosocomial vancomycin-resistant Enterococcus faecium meningitis in the setting of hyperinfection with Strongyloides stercoralis that was successfully treated with linezolid. We also review the previously reported cases of vancomycin-resistant E. faecium meningitis.

Original language	English
Pages (from-to)	477-482
Number of pages	6
Journal	Clinical Infectious Diseases
Volume	33
Issue number	4
DOIs	https://doi.org/10.1086/321896
State	Published - 15 Aug 2001
Externally published	Yes

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abstract = "Enterococci cause serious illness in immunocompromised patients and severely ill, hospitalized patients. Resistance to vancomycin has increased in frequency during the past few years. Limited therapeutic options are available for vancomycin-resistant enterococcal infections and the optimum therapy has not been established. We report a case of nosocomial vancomycin-resistant Enterococcus faecium meningitis in the setting of hyperinfection with Strongyloides stercoralis that was successfully treated with linezolid. We also review the previously reported cases of vancomycin-resistant E. faecium meningitis.",

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AB - Enterococci cause serious illness in immunocompromised patients and severely ill, hospitalized patients. Resistance to vancomycin has increased in frequency during the past few years. Limited therapeutic options are available for vancomycin-resistant enterococcal infections and the optimum therapy has not been established. We report a case of nosocomial vancomycin-resistant Enterococcus faecium meningitis in the setting of hyperinfection with Strongyloides stercoralis that was successfully treated with linezolid. We also review the previously reported cases of vancomycin-resistant E. faecium meningitis.

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Vancomycin-resistant Enterococcus faecium meningitis successfully managed with linezolid: Case report and review of the literature

Abstract

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