@article{66bd4ea33b144d02bffeb0af81ceb05e,
title = "VALUE OF THYROID-STIMULATING-ANTIBODY DETERMINATIONS IN PREDICTING SHORT-TERM THYROTOXIC RELAPSE IN GRAVES' DISEASE",
abstract = "Thirty consecutive patients with hyper-thyroid Graves' disease received a 6-month course of antithyroid drugs. Sixteen patients relapsed within 6 months of the withdrawal of antithyroid therapy. All patients with high levels of thyroid-stimulating antibodies (TSAb) at the time of drug withdrawal relapsed within 2 months of discontinuing the antithyroid treatment while all patients with low or undetectable TSAb activity at the time of drug withdrawal remained in remission. It was not possible to predict the disease course in patients who had intermediate levels of TSAb when antithyroid therapy was stopped.",
author = "Davies, {T. F.} and Evered, {D. C.} and Smith, {B. Rees} and Yeo, {P. P.B.} and F. Clark and R. Hall",
note = "Funding Information: We thank the surgeons of the Northern region for specimens of thy. roid tissue, Dr T. Bird and the department of hzmatotogy, Newcastle General Hospital, for the thyroid antibody determinations, and Prof. A. L. Latner for helpful advice. This study was supported by grants from the Medical Research Council, the North of England Campaign for Cancer Research, the Ernest and Minnie Dawson Cancer Trust, (Teaching), and G. D. Searle (Diagnostics) Ltd.the Research Committee of the Newcastle Area Health Authority",
year = "1977",
month = jun,
day = "4",
doi = "10.1016/S0140-6736(77)92719-2",
language = "English",
volume = "309",
pages = "1181--1182",
journal = "The Lancet",
issn = "0140-6736",
publisher = "Elsevier Ltd.",
number = "8023",
}