TY - JOUR
T1 - Value of hyaluronidase in ocular surgical akinesia
AU - Mindel, J. S.
N1 - Funding Information:
From the Ophthalmology Section of the Bronx Veterans Hospital, New York, and the Pharmacology Department of Mount Sinai School of Medicine, New York. This study was supported in part by the Medical Research Service of the Veterans Administration and National Eye Institute Grant EY 00340. Dr. Mindel is supported by a Research Career Development Award of the National Eye Institute. Reprint requests to Joel S. Mindel, M.D., Department of Pharmacology, Basic Science Building, Mount Sinai School of Medicine, Fifth Ave. and 100th St., New York, NY 10029.
PY - 1978
Y1 - 1978
N2 - In a study of 27 cases of surgery for cataract extraction, mepivacaine 2% with hyaluronidase was found to shorten the induction times of facial nerve and retrobulbar blocks when compared to injections of mepivacaine 2% alone. The mean induction time of facial nerve blocks with hyaluronidase was 1.3 ± 0.4 min. This was significantly (P < 01) shorter than the mean induction time without hyaluronidase, 2.9 ± 1.8 min. The use of hyaluronidase significantly (P < .02) shortened the induction time of retrobulbar blocks. The median induction time with hyaluronidase was 3 min, whereas that without hyaluronidase was 10 min. However, the use of hyaluronidase did not significantly (.25 < P < .50) alter the success rate of retrobulbar blocks.
AB - In a study of 27 cases of surgery for cataract extraction, mepivacaine 2% with hyaluronidase was found to shorten the induction times of facial nerve and retrobulbar blocks when compared to injections of mepivacaine 2% alone. The mean induction time of facial nerve blocks with hyaluronidase was 1.3 ± 0.4 min. This was significantly (P < 01) shorter than the mean induction time without hyaluronidase, 2.9 ± 1.8 min. The use of hyaluronidase significantly (P < .02) shortened the induction time of retrobulbar blocks. The median induction time with hyaluronidase was 3 min, whereas that without hyaluronidase was 10 min. However, the use of hyaluronidase did not significantly (.25 < P < .50) alter the success rate of retrobulbar blocks.
UR - https://www.scopus.com/pages/publications/0017805453
U2 - 10.1016/S0002-9394(14)77097-7
DO - 10.1016/S0002-9394(14)77097-7
M3 - Article
C2 - 350052
AN - SCOPUS:0017805453
SN - 0002-9394
VL - 85
SP - 643
EP - 646
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 5 I
ER -