Valproic acid and pregnancy

  • Jakob Christensen
  • , Sean Tchanho Hwang
  • , C. L. Harden

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

A 26-year-old woman (G2P1) is referred to you for consultation. She is in her second month of pregnancy and on valproic acid 1000 mg twice daily for her medically stable Juvenile Myoclonic Epilepsy. She has not had any seizure recurrences in the past year. Would you lower valproic acid; discontinue it or switch to another seizure medication during her current pregnancy? If you would switch her seizure medication, what would you switch to and how do you manage her epilepsy during this pregnancy?.

Original languageEnglish
Title of host publicationControversies in Caring for Women with Epilepsy
Subtitle of host publicationSorting Through the Evidence
PublisherSpringer International Publishing
Pages115-123
Number of pages9
ISBN (Electronic)9783319291703
ISBN (Print)9783319291680
DOIs
StatePublished - 1 Jan 2016
Externally publishedYes

Keywords

  • Anticonvulsant
  • Antiepileptic
  • Antiepileptic drugs
  • Birth outcome
  • Cognitive development
  • Congenital malformations
  • Depakote
  • Epilepsy
  • Juvenile
  • Lamotrigine
  • Levetiracetam
  • Malformation
  • Myoclonic
  • Pregnancy
  • Teratogenicity
  • Topiramate
  • Valproate
  • Valproic acid

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