Validation of the PTSD Checklist-Civilian Version in survivors of bone marrow transplantation

Meredith Y. Smith, William Redd, Katherine DuHamel, Suzanne Johnson Vickberg, Patricia Ricketts

Research output: Contribution to journalArticlepeer-review

143 Scopus citations


Life-threatening illness now qualifies as a precipitating stressor for posttraumatic stress disorder (PTSD). We examined the validity of the PTSD Checklist-Civilian Version (PCL-C; Weathers, Litz, Herman, Juska, and Keane, 1993), a brief 17-item inventory of PTSD-like symptoms, in a sample of 111 adults who had undergone bone marrow transplantation an average of 4.04 years previously. Exploratory factor analysis of the PCL-C identified four distinct patterns of symptom responses: Numbing-Hyperarousal, Dreams-Memories of the Cancer Treatment, General Hyperarousal, Responses to Cancer-Related Reminders and Avoidance-Numbing. Respondents meeting PTSD symptom criteria on the PCL-C had significantly lower physical, role, and social functioning, greater distress and anxiety, and significantly more intrusive and avoidant responses than individuals who did not meet PTSD symptom criteria.

Original languageEnglish
Pages (from-to)485-499
Number of pages15
JournalJournal of Traumatic Stress
Issue number3
StatePublished - 1999


  • Bone marrow transplant
  • PTSD Checklist-Civilian Version (PCL-C)
  • Posttraumatic stress disorder (PTSD)
  • Psychometrics
  • Quality of life


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