Vaccine-breakthrough infection by the SARS-CoV-2 omicron variant elicits broadly cross-reactive immune responses

Runhong Zhou; Kelvin Kai Wang To; Qiaoli Peng; Jacky Man Chun Chan; Haode Huang; Dawei Yang; Bosco Hoi Shiu Lam; Vivien Wai Man Chuang; Jian Piao Cai; Na Liu; Ka Kit Au; Owen Tak Yin Tsang; Kwok Yung Yuen; Zhiwei Chen

doi:10.1002/ctm2.720

Vaccine-breakthrough infection by the SARS-CoV-2 omicron variant elicits broadly cross-reactive immune responses

Runhong Zhou, Kelvin Kai Wang To, Qiaoli Peng, Jacky Man Chun Chan, Haode Huang, Dawei Yang, Bosco Hoi Shiu Lam, Vivien Wai Man Chuang, Jian Piao Cai, Na Liu, Ka Kit Au, Owen Tak Yin Tsang, Kwok Yung Yuen, Zhiwei Chen

Research output: Contribution to journal › Letter › peer-review

27 Scopus citations

Original language	English
Article number	e720
Journal	Clinical and Translational Medicine
Volume	12
Issue number	1
DOIs	https://doi.org/10.1002/ctm2.720
State	Published - Jan 2022
Externally published	Yes

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10.1002/ctm2.720

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Zhou, R., To, K. K. W., Peng, Q., Chan, J. M. C., Huang, H., Yang, D., Lam, B. H. S., Chuang, V. W. M., Cai, J. P., Liu, N., Au, K. K., Tsang, O. T. Y., Yuen, K. Y., & Chen, Z. (2022). Vaccine-breakthrough infection by the SARS-CoV-2 omicron variant elicits broadly cross-reactive immune responses. Clinical and Translational Medicine, 12(1), Article e720. https://doi.org/10.1002/ctm2.720

@article{387aa4a56b9040dd950a8d9fca3f67f5,

title = "Vaccine-breakthrough infection by the SARS-CoV-2 omicron variant elicits broadly cross-reactive immune responses",

author = "Runhong Zhou and To, {Kelvin Kai Wang} and Qiaoli Peng and Chan, {Jacky Man Chun} and Haode Huang and Dawei Yang and Lam, {Bosco Hoi Shiu} and Chuang, {Vivien Wai Man} and Cai, {Jian Piao} and Na Liu and Au, {Ka Kit} and Tsang, {Owen Tak Yin} and Yuen, {Kwok Yung} and Zhiwei Chen",

note = "Funding Information: This study was supported by the Hong Kong Research Grants Council Collaborative Research Fund (C7156‐20GF, C1134‐20GF and C5110‐20GF) and Health and Medical Research Fund (19181012); Shenzhen Science and Technology Program (JSGG20200225151410198 and JCYJ20210324131610027); the Hong Kong Health@InnoHK, Innovation and Technology Commission; and the China National Program on Key Research Project (2020YFC0860600, 2020YFA0707500 and 2020YFA0707504); and donations from the Friends of Hope Education Fund. Z.C.{\textquoteright}s team was also partly supported by the Hong Kong Theme‐Based Research Scheme (T11‐706/18‐N and T11‐709/21‐N). We sincerely thank Drs. David D. Ho and Pengfei Wang for the expression plasmids encoding for D614 G, alpha and beta variants, and Dr. Linqi Zhang for the delta variant plasmid. ",

year = "2022",

month = jan,

doi = "10.1002/ctm2.720",

language = "English",

volume = "12",

journal = "Clinical and Translational Medicine",

issn = "2001-1326",

publisher = "John Wiley and Sons Inc.",

number = "1",

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T1 - Vaccine-breakthrough infection by the SARS-CoV-2 omicron variant elicits broadly cross-reactive immune responses

AU - Zhou, Runhong

AU - To, Kelvin Kai Wang

AU - Peng, Qiaoli

AU - Chan, Jacky Man Chun

AU - Huang, Haode

AU - Yang, Dawei

AU - Lam, Bosco Hoi Shiu

AU - Chuang, Vivien Wai Man

AU - Cai, Jian Piao

AU - Liu, Na

AU - Au, Ka Kit

AU - Tsang, Owen Tak Yin

AU - Yuen, Kwok Yung

AU - Chen, Zhiwei

N1 - Funding Information: This study was supported by the Hong Kong Research Grants Council Collaborative Research Fund (C7156‐20GF, C1134‐20GF and C5110‐20GF) and Health and Medical Research Fund (19181012); Shenzhen Science and Technology Program (JSGG20200225151410198 and JCYJ20210324131610027); the Hong Kong Health@InnoHK, Innovation and Technology Commission; and the China National Program on Key Research Project (2020YFC0860600, 2020YFA0707500 and 2020YFA0707504); and donations from the Friends of Hope Education Fund. Z.C.’s team was also partly supported by the Hong Kong Theme‐Based Research Scheme (T11‐706/18‐N and T11‐709/21‐N). We sincerely thank Drs. David D. Ho and Pengfei Wang for the expression plasmids encoding for D614 G, alpha and beta variants, and Dr. Linqi Zhang for the delta variant plasmid.

PY - 2022/1

Y1 - 2022/1

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DO - 10.1002/ctm2.720

M3 - Letter

C2 - 35083867

AN - SCOPUS:85124107697

SN - 2001-1326

VL - 12

JO - Clinical and Translational Medicine

JF - Clinical and Translational Medicine

IS - 1

M1 - e720

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