Abstract
Hailey-Hailey Disease is a rare disease associated with mutation of the ATP2C1 gene characterized by skin blistering and erosion. Here, we report a case of a patient with Hailey-Hailey disease who significantly improved after treatment with upadacitinib. A 55-year-old male with biopsy-confirmed Hailey-Hailey disease presented with a 20-year history of ill-defined, brightly erythematous, painful patches initially on the neck and subsequently involving the penile shaft. Following treatment with 30 mg of upadacitinib, the patient’s neck ulcer gradually reepithelized. This case adds to the growing body of literature supporting the use of Janus kinase inhibitors as a therapeutic modality for this condition.
Original language | English |
---|---|
Pages (from-to) | 2021-2024 |
Number of pages | 4 |
Journal | SKIN: Journal of Cutaneous Medicine |
Volume | 8 |
Issue number | 6 |
DOIs | |
State | Published - Nov 2024 |
Keywords
- hailey hailey disease
- janus kinase inhibitors
- upadacitinib