Utility of the electrocardiogram in drug overdose and poisoning: Theoretical considerations and clinical implications

Christopher Yates, Alex F. Manini

Research output: Contribution to journalReview articlepeer-review

23 Scopus citations

Abstract

The ECG is a rapidly available clinical tool that can help clinicians manage poisoned patients. Specific myocardial effects of cardiotoxic drugs have well-described electrocardiographic manifestations. In the practice of clinical toxicology, classic ECG changes may hint at blockade of ion channels, alterations of adrenergic tone, or dysfunctional metabolic activity of the myocardium. This review will offer a structured approach to ECG interpretation in poisoned patients with a focus on clinical implications and ECG-based management recommendations in the initial evaluation of patients with acute cardiotoxicity.

Original languageEnglish
Pages (from-to)137-151
Number of pages15
JournalCurrent Cardiology Reviews
Volume8
Issue number2
DOIs
StatePublished - 2012

Keywords

  • Electrocardiography
  • Poisoning
  • Toxicology

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