Utility of teledermatopathology for intraoperative margin assessment of melanoma in situ, lentigo maligna type: A 6 year community practice experience

Patrick O. Emanuel, Rajan Patel, Jonathan Zwi, Du Cheng, Mark Izzard

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Background: Achieving negative margins for melanoma in situ, lentigo maligna type can be challenging, particularly on cosmetically sensitive areas. Objective: To assess the utility of intraoperative frozen section margin assessment using a teledermatopathology system in the treatment of head and neck lentigo maligna. Methods and materials: Over a 6 year period, 96 patients with lentigo maligna had surgical excisions. The margins were assessed intraoperatively with frozen sections prepared in the manner used in Mohs surgery. The surgeon guided the frozen section slides around the margin while a dermatopathologist assessed the margin remotely. Results: In 2/96 (2.1%) cases, the safety margin was positive (frozen sections were false negative). In 1 further case (1%) there was a recurrence of the melanoma 13 months following the excision. Conclusion: The described method is effective in treating melanoma in situ, lentigo maligna type with clearance rates similar to previous studies for Mohs surgery.

Original languageEnglish
Pages (from-to)1140-1144
Number of pages5
JournalEuropean Journal of Surgical Oncology
Volume47
Issue number5
DOIs
StatePublished - May 2021
Externally publishedYes

Keywords

  • Frozen section
  • Lentigo maligna
  • Margin control surgery
  • Melanoma
  • Mohs

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