Using ranibizumab to successfully treat choroidal neovascularization in a patient with persistent placoid maculopathy

Emily C. Waisbren; Joseph Ho; Lindsay M. Smithen; Lawrence A. Yannuzzi; Jay S. Duker

doi:10.1097/ICB.0b013e3181c59791

Using ranibizumab to successfully treat choroidal neovascularization in a patient with persistent placoid maculopathy

Emily C. Waisbren, Joseph Ho, Lindsay M. Smithen, Lawrence A. Yannuzzi, Jay S. Duker

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Purpose: The purpose of this study was to report the successful treatment of persistent placoid maculopathy with intravitreal ranibizumab. Methods: A 60-year-old man with an 8-year history of blurry vision was diagnosed with bilateral persistent placoid maculopathy complicated by a choroidal neovascular membrane. The left eye received two laser photocoagulation treatments. The right eye was injected twice with intravitreal bevacizumab and then 3 times with intravitreal ranibizumab over the course of 1 year. Results: Visual acuity in the left eye dropped from 20/30 to 20/100 despite gradual resolution of fluid. However, visual acuity in the right eye improved from 20/50 to 20/25 where it remained for 24 months after the last injection. Conclusion: Ranibizumab seems to be efficacious in the treatment of choroidal neovascularization in persistent placoid maculopathy.

Original language	English
Pages (from-to)	211-215
Number of pages	5
Journal	Retinal Cases and Brief Reports
Volume	4
Issue number	3
DOIs	https://doi.org/10.1097/ICB.0b013e3181c59791
State	Published - Jun 2010
Externally published	Yes

Keywords

Avastin
Bevacizumab
Lucentis
Persistent placoid maculopathy
Ranibizumab

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10.1097/ICB.0b013e3181c59791

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title = "Using ranibizumab to successfully treat choroidal neovascularization in a patient with persistent placoid maculopathy",

abstract = "Purpose: The purpose of this study was to report the successful treatment of persistent placoid maculopathy with intravitreal ranibizumab. Methods: A 60-year-old man with an 8-year history of blurry vision was diagnosed with bilateral persistent placoid maculopathy complicated by a choroidal neovascular membrane. The left eye received two laser photocoagulation treatments. The right eye was injected twice with intravitreal bevacizumab and then 3 times with intravitreal ranibizumab over the course of 1 year. Results: Visual acuity in the left eye dropped from 20/30 to 20/100 despite gradual resolution of fluid. However, visual acuity in the right eye improved from 20/50 to 20/25 where it remained for 24 months after the last injection. Conclusion: Ranibizumab seems to be efficacious in the treatment of choroidal neovascularization in persistent placoid maculopathy.",

keywords = "Avastin, Bevacizumab, Lucentis, Persistent placoid maculopathy, Ranibizumab",

author = "Waisbren, {Emily C.} and Joseph Ho and Smithen, {Lindsay M.} and Yannuzzi, {Lawrence A.} and Duker, {Jay S.}",

year = "2010",

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doi = "10.1097/ICB.0b013e3181c59791",

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T1 - Using ranibizumab to successfully treat choroidal neovascularization in a patient with persistent placoid maculopathy

AU - Waisbren, Emily C.

AU - Ho, Joseph

AU - Smithen, Lindsay M.

AU - Yannuzzi, Lawrence A.

AU - Duker, Jay S.

PY - 2010/6

Y1 - 2010/6

N2 - Purpose: The purpose of this study was to report the successful treatment of persistent placoid maculopathy with intravitreal ranibizumab. Methods: A 60-year-old man with an 8-year history of blurry vision was diagnosed with bilateral persistent placoid maculopathy complicated by a choroidal neovascular membrane. The left eye received two laser photocoagulation treatments. The right eye was injected twice with intravitreal bevacizumab and then 3 times with intravitreal ranibizumab over the course of 1 year. Results: Visual acuity in the left eye dropped from 20/30 to 20/100 despite gradual resolution of fluid. However, visual acuity in the right eye improved from 20/50 to 20/25 where it remained for 24 months after the last injection. Conclusion: Ranibizumab seems to be efficacious in the treatment of choroidal neovascularization in persistent placoid maculopathy.

AB - Purpose: The purpose of this study was to report the successful treatment of persistent placoid maculopathy with intravitreal ranibizumab. Methods: A 60-year-old man with an 8-year history of blurry vision was diagnosed with bilateral persistent placoid maculopathy complicated by a choroidal neovascular membrane. The left eye received two laser photocoagulation treatments. The right eye was injected twice with intravitreal bevacizumab and then 3 times with intravitreal ranibizumab over the course of 1 year. Results: Visual acuity in the left eye dropped from 20/30 to 20/100 despite gradual resolution of fluid. However, visual acuity in the right eye improved from 20/50 to 20/25 where it remained for 24 months after the last injection. Conclusion: Ranibizumab seems to be efficacious in the treatment of choroidal neovascularization in persistent placoid maculopathy.

KW - Avastin

KW - Bevacizumab

KW - Lucentis

KW - Persistent placoid maculopathy

KW - Ranibizumab

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Using ranibizumab to successfully treat choroidal neovascularization in a patient with persistent placoid maculopathy

Abstract

Keywords

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