Abstract
In this issue of Neuron, innovative new modifications to opioid receptors are used to expand the tools available to modulate neuronal activity. Vardy etal. (2015) describe a new "DREADD" chemogenetic tool based on the inhibitory κ opioid receptor (KORD) that can be used in conjunction with already-availableDREADDs. Siuda etal. (2015) report the development of "opto-MOR," a light-activatable μ opioidreceptor (MOR) chimera that can be used to better understand the complexities of MOR signaling.
Original language | English |
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Pages (from-to) | 853-855 |
Number of pages | 3 |
Journal | Neuron |
Volume | 86 |
Issue number | 4 |
DOIs | |
State | Published - 20 May 2015 |