In this issue of Neuron, innovative new modifications to opioid receptors are used to expand the tools available to modulate neuronal activity. Vardy etal. (2015) describe a new "DREADD" chemogenetic tool based on the inhibitory κ opioid receptor (KORD) that can be used in conjunction with already-availableDREADDs. Siuda etal. (2015) report the development of "opto-MOR," a light-activatable μ opioidreceptor (MOR) chimera that can be used to better understand the complexities of MOR signaling.

Original languageEnglish
Pages (from-to)853-855
Number of pages3
Issue number4
StatePublished - 20 May 2015


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