Using neuroimaging to help predict the onset of psychosis

George Gifford, Nicolas Crossley, Paolo Fusar-Poli, Hugo G. Schnack, René S. Kahn, Nikolaos Koutsouleris, Tyrone D. Cannon, Philip McGuire

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

The aim of this review is to assess the potential for neuroimaging measures to facilitate prediction of the onset of psychosis. Research in this field has mainly involved people at ‘ultra-high risk’ (UHR) of psychosis, who have a very high risk of developing a psychotic disorder within a few years of presentation to mental health services. The review details the key findings and developments in this area to date and examines the methodological and logistical challenges associated with making predictions in an individual subject in a clinical setting.

Original languageEnglish
Pages (from-to)209-217
Number of pages9
JournalNeuroImage
Volume145
DOIs
StatePublished - 15 Jan 2017
Externally publishedYes

Keywords

  • Graph analysis
  • Machine learning
  • Multicentre neuroimaging studies
  • Multimodal neuroimaging
  • Psychosis prediction
  • Support vector machines
  • Ultra high-risk of psychosis

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