Using molecular markers in sputum for the early detection of lung cancer: A review

Timothy C. Kennedy; Fred R. Hirsch

doi:10.1016/j.lungcan.2004.07.996

Using molecular markers in sputum for the early detection of lung cancer: A review

Timothy C. Kennedy, Fred R. Hirsch

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

Recent exciting advances have been made in identifying potential molecular markers in sputum which may soon be ready for validation trials to indicate high risk for lung cancer, especially central airway squamous cell lung cancer. Hopefully, a set of biomarkers will be identified with higher sensitivity, specificity, and enough lead-time compared to traditional cytopathology to justify endobronchial evaluation and local therapy to help reduce lung-cancer mortality in high-risk patients.

Original language	English
Pages (from-to)	S21-S27
Journal	Lung Cancer
Volume	45
Issue number	SUPPL. 2
DOIs	https://doi.org/10.1016/j.lungcan.2004.07.996
State	Published - Aug 2004
Externally published	Yes

Keywords

Biological markers
Non-small-cell lung carcinoma
Sputum

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10.1016/j.lungcan.2004.07.996

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title = "Using molecular markers in sputum for the early detection of lung cancer: A review",

abstract = "Recent exciting advances have been made in identifying potential molecular markers in sputum which may soon be ready for validation trials to indicate high risk for lung cancer, especially central airway squamous cell lung cancer. Hopefully, a set of biomarkers will be identified with higher sensitivity, specificity, and enough lead-time compared to traditional cytopathology to justify endobronchial evaluation and local therapy to help reduce lung-cancer mortality in high-risk patients.",

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AB - Recent exciting advances have been made in identifying potential molecular markers in sputum which may soon be ready for validation trials to indicate high risk for lung cancer, especially central airway squamous cell lung cancer. Hopefully, a set of biomarkers will be identified with higher sensitivity, specificity, and enough lead-time compared to traditional cytopathology to justify endobronchial evaluation and local therapy to help reduce lung-cancer mortality in high-risk patients.

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KW - Non-small-cell lung carcinoma

KW - Sputum

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Using molecular markers in sputum for the early detection of lung cancer: A review

Abstract

Keywords

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