Use of whole-body FDG PET-CT to aid in the diagnosis of occult sarcoidosis

Bradford L. Tannen; Nasrin V. Ghesani; Larry Frohman; Joel D. Eichler; Pierre D. Maldjian; David S. Chu

doi:10.1080/09273940801899798

Use of whole-body FDG PET-CT to aid in the diagnosis of occult sarcoidosis

Bradford L. Tannen, Nasrin V. Ghesani, Larry Frohman, Joel D. Eichler, Pierre D. Maldjian, David S. Chu

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

Purpose: To report a case where combined whole-body Fluorine-18 fluorodeoxyglucose (FDG) PET-CT scanning was used to aid in the diagnosis of a patient with occult sarcoidosis. Design: Case report. Methods: FDG PET-CT scanning was performed in a patient who presented with persistent bilateral panuveitis after cataract surgery and had undergone an extensive negative workup. Results: FDG PET-CT scanning demonstrated extensive mediastinal adenopathy. Biopsy showed a non-caseating granuloma with associated giant cell formation consistent with a diagnosis of sarcoidosis. Conclusions: FDG PET-CT scanning generates tomographic scans with excellent sensitivity, spatial resolution, and anatomical landmark identification and may be useful in the workup of idiopathic uveitis.

Original language	English
Pages (from-to)	25-27
Number of pages	3
Journal	Ocular Immunology and Inflammation
Volume	16
Issue number	1-2
DOIs	https://doi.org/10.1080/09273940801899798
State	Published - Jan 2008
Externally published	Yes

Keywords

FDG PET-CT
Sarcoidosis
Uveitis

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10.1080/09273940801899798

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title = "Use of whole-body FDG PET-CT to aid in the diagnosis of occult sarcoidosis",

abstract = "Purpose: To report a case where combined whole-body Fluorine-18 fluorodeoxyglucose (FDG) PET-CT scanning was used to aid in the diagnosis of a patient with occult sarcoidosis. Design: Case report. Methods: FDG PET-CT scanning was performed in a patient who presented with persistent bilateral panuveitis after cataract surgery and had undergone an extensive negative workup. Results: FDG PET-CT scanning demonstrated extensive mediastinal adenopathy. Biopsy showed a non-caseating granuloma with associated giant cell formation consistent with a diagnosis of sarcoidosis. Conclusions: FDG PET-CT scanning generates tomographic scans with excellent sensitivity, spatial resolution, and anatomical landmark identification and may be useful in the workup of idiopathic uveitis.",

keywords = "FDG PET-CT, Sarcoidosis, Uveitis",

author = "Tannen, {Bradford L.} and Ghesani, {Nasrin V.} and Larry Frohman and Eichler, {Joel D.} and Maldjian, {Pierre D.} and Chu, {David S.}",

note = "Funding Information: Received 10 August, 2007; accepted November 9, 2007. This work was funded in part by Research to Prevent Blindness and a grant from The Eye Institute of New Jersey.",

year = "2008",

month = jan,

doi = "10.1080/09273940801899798",

language = "English",

volume = "16",

pages = "25--27",

journal = "Ocular Immunology and Inflammation",

issn = "0927-3948",

publisher = "Taylor and Francis Ltd.",

number = "1-2",

}

TY - JOUR

T1 - Use of whole-body FDG PET-CT to aid in the diagnosis of occult sarcoidosis

AU - Tannen, Bradford L.

AU - Ghesani, Nasrin V.

AU - Frohman, Larry

AU - Eichler, Joel D.

AU - Maldjian, Pierre D.

AU - Chu, David S.

N1 - Funding Information: Received 10 August, 2007; accepted November 9, 2007. This work was funded in part by Research to Prevent Blindness and a grant from The Eye Institute of New Jersey.

PY - 2008/1

Y1 - 2008/1

N2 - Purpose: To report a case where combined whole-body Fluorine-18 fluorodeoxyglucose (FDG) PET-CT scanning was used to aid in the diagnosis of a patient with occult sarcoidosis. Design: Case report. Methods: FDG PET-CT scanning was performed in a patient who presented with persistent bilateral panuveitis after cataract surgery and had undergone an extensive negative workup. Results: FDG PET-CT scanning demonstrated extensive mediastinal adenopathy. Biopsy showed a non-caseating granuloma with associated giant cell formation consistent with a diagnosis of sarcoidosis. Conclusions: FDG PET-CT scanning generates tomographic scans with excellent sensitivity, spatial resolution, and anatomical landmark identification and may be useful in the workup of idiopathic uveitis.

AB - Purpose: To report a case where combined whole-body Fluorine-18 fluorodeoxyglucose (FDG) PET-CT scanning was used to aid in the diagnosis of a patient with occult sarcoidosis. Design: Case report. Methods: FDG PET-CT scanning was performed in a patient who presented with persistent bilateral panuveitis after cataract surgery and had undergone an extensive negative workup. Results: FDG PET-CT scanning demonstrated extensive mediastinal adenopathy. Biopsy showed a non-caseating granuloma with associated giant cell formation consistent with a diagnosis of sarcoidosis. Conclusions: FDG PET-CT scanning generates tomographic scans with excellent sensitivity, spatial resolution, and anatomical landmark identification and may be useful in the workup of idiopathic uveitis.

KW - FDG PET-CT

KW - Sarcoidosis

KW - Uveitis

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JO - Ocular Immunology and Inflammation

JF - Ocular Immunology and Inflammation

IS - 1-2

ER -

Use of whole-body FDG PET-CT to aid in the diagnosis of occult sarcoidosis

Abstract

Keywords

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