Use of recombinant-hirudin in pulmonary thromboendarterectomy

Fraser D. Rubens, Mitchell Sabloff, Philip S. Wells, Michael Bourke

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


A patient with chronic thromboembolic pulmonary hypertension and heparin-induced thrombocytopenia successfully underwent pulmonary thromboendarterectomy with circulatory arrest, using recombinant hirudin as an alternative anticoagulant to heparin. Techniques for administration as well as monitoring of this drug's effects are discussed. (C) 2000 by The Society of Thoracic Surgeons.

Original languageEnglish
Pages (from-to)1942-1943
Number of pages2
JournalAnnals of Thoracic Surgery
Issue number6
StatePublished - Jun 2000
Externally publishedYes


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