Use of preimplantation genetic testing for monogenic defects (PGT-M) for adult-onset conditions: an Ethics Committee opinion

Ethics Committee of the American Society for Reproductive Medicine

doi:10.1016/j.fertnstert.2018.04.003

Use of preimplantation genetic testing for monogenic defects (PGT-M) for adult-onset conditions: an Ethics Committee opinion

Ethics Committee of the American Society for Reproductive Medicine

Icahn School of Medicine at Mount Sinai

Research output: Contribution to journal › Article › peer-review

78 Scopus citations

Abstract

Preimplantation genetic testing for monogenic diseases for adult-onset conditions is ethically permissible for a range of conditions including when the condition is serious and no safe, effective interventions are available. The Committee strongly recommends that a genetic counselor experienced with PGT-M counsel patients considering such procedures. This document replaces the document titled “Use of preimplantation genetic diagnosis for serious adult-onset conditions: a committee opinion,” last published in Fertil Steril 2013;100;54-7. Earn online CME credit related to this document at www.asrm.org/elearn

Original language	English
Pages (from-to)	989-992
Number of pages	4
Journal	Fertility and Sterility
Volume	109
Issue number	6
DOIs	https://doi.org/10.1016/j.fertnstert.2018.04.003
State	Published - Jun 2018

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10.1016/j.fertnstert.2018.04.003

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title = "Use of preimplantation genetic testing for monogenic defects (PGT-M) for adult-onset conditions: an Ethics Committee opinion",

abstract = "Preimplantation genetic testing for monogenic diseases for adult-onset conditions is ethically permissible for a range of conditions including when the condition is serious and no safe, effective interventions are available. The Committee strongly recommends that a genetic counselor experienced with PGT-M counsel patients considering such procedures. This document replaces the document titled “Use of preimplantation genetic diagnosis for serious adult-onset conditions: a committee opinion,” last published in Fertil Steril 2013;100;54-7. Earn online CME credit related to this document at www.asrm.org/elearn",

author = "{Ethics Committee of the American Society for Reproductive Medicine} and Judith Daar and Jean Benward and Lee Collins and Joseph Davis and Owen Davis and Leslie Francis and Elena Gates and Elizabeth Ginsburg and Susan Gitlin and Sigal Klipstein and Laurence McCullough and Richard Paulson and Richard Reindollar and Ginny Ryan and Mark Sauer and Sean Tipton and Lynn Westphal and Julianne Zweifel",

note = "Publisher Copyright: {\textcopyright} 2018 American Society for Reproductive Medicine",

year = "2018",

month = jun,

doi = "10.1016/j.fertnstert.2018.04.003",

language = "English",

volume = "109",

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journal = "Fertility and Sterility",

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T1 - Use of preimplantation genetic testing for monogenic defects (PGT-M) for adult-onset conditions

T2 - an Ethics Committee opinion

AU - Ethics Committee of the American Society for Reproductive Medicine

AU - Daar, Judith

AU - Benward, Jean

AU - Collins, Lee

AU - Davis, Joseph

AU - Davis, Owen

AU - Francis, Leslie

AU - Gates, Elena

AU - Ginsburg, Elizabeth

AU - Gitlin, Susan

AU - Klipstein, Sigal

AU - McCullough, Laurence

AU - Paulson, Richard

AU - Reindollar, Richard

AU - Ryan, Ginny

AU - Sauer, Mark

AU - Tipton, Sean

AU - Westphal, Lynn

AU - Zweifel, Julianne

PY - 2018/6

Y1 - 2018/6

N2 - Preimplantation genetic testing for monogenic diseases for adult-onset conditions is ethically permissible for a range of conditions including when the condition is serious and no safe, effective interventions are available. The Committee strongly recommends that a genetic counselor experienced with PGT-M counsel patients considering such procedures. This document replaces the document titled “Use of preimplantation genetic diagnosis for serious adult-onset conditions: a committee opinion,” last published in Fertil Steril 2013;100;54-7. Earn online CME credit related to this document at www.asrm.org/elearn

AB - Preimplantation genetic testing for monogenic diseases for adult-onset conditions is ethically permissible for a range of conditions including when the condition is serious and no safe, effective interventions are available. The Committee strongly recommends that a genetic counselor experienced with PGT-M counsel patients considering such procedures. This document replaces the document titled “Use of preimplantation genetic diagnosis for serious adult-onset conditions: a committee opinion,” last published in Fertil Steril 2013;100;54-7. Earn online CME credit related to this document at www.asrm.org/elearn

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U2 - 10.1016/j.fertnstert.2018.04.003

DO - 10.1016/j.fertnstert.2018.04.003

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AN - SCOPUS:85048765129

SN - 0015-0282

VL - 109

SP - 989

EP - 992

JO - Fertility and Sterility

JF - Fertility and Sterility

IS - 6

ER -

Use of preimplantation genetic testing for monogenic defects (PGT-M) for adult-onset conditions: an Ethics Committee opinion

Abstract

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