Use of paracervical block before laparoscopic supracervical hysterectomy

Rachel L.Barr Grzesh, Alejandro D. Treszezamsky, Suzanne S. Fenske, Lauren G. Rascoff, Erin L. Moshier, Charles Ascher-Walsh

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5 Scopus citations


Background and Objective: Some patients who un-dergo laparoscopic hysterectomy request overnight admission for pain management, thus increasing costs for a surgery that is safe for same-day discharge. We wanted to evaluate whether a paracervical block of bupivacaine with epinephrine before laparoscopic supracervical hysterectomy would decrease overnight admission rates, postoperative pain, and pain medication requirement Methods: This was a randomized, double-blind, placebo-controlled, parallel-group trial (Canadian Task Force classification I) at an academic medical center. Patients undergoing laparoscopic supracervical hysterectomy were randomized to a 20-mL paracervical injection of either 0.25% bupivacaine with epinephrine or 20 mL normal saline before skin incision. All providers, except the circulating nurse, were blinded. The primary outcome was overnight hospital admission rate. Secondary outcomes included postoperative pain medication use and pain scores. Analysis included t test, x2, Wilcoxon, and ANOVA. Results: One hundred thirty-two patients were en-rolled—68 in the treatment group and 64 in the placebo group. Demographics were similar between groups. The unplanned overnight admission rate was 34% for the treatment group and 27% for the placebo group (P < .25). After discharge, the treatment group used on average 8.5 tablets of narcotics, whereas the placebo group used 11.7 tablets (P < .07). The treatment group took 13.1 tablets of nonnarcotic analgesics compared to 11.2 in the placebo group (P < .57). Both groups reported similar pain scores. Conclusion: Paracervical block with bupivacaine and epinephrine before laparoscopic supracervical hysterectomy did not decrease overnight admission rate or affect postoperative pain. Postoperative opiate use was minimally decreased.

Original languageEnglish
Article numbere2018.00023
JournalJournal of the Society of Laparoendoscopic Surgeons
Issue number3
StatePublished - 1 Jul 2018


  • Laparoscopic supracervical hysterectomy
  • Overnight admission
  • Paracervical block
  • Post-operative pain
  • Preemptive analgesia


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