Use of oxygen inhalation in evaluation of respiratory acidosis in patients with apparent metabolic alkalosis

Albert Miller, Alvin S. Teirstein, Joel Duberstein, E. Leslie Chusid, Mortimer E. Bader, Richard A. Bader

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Respiratory failure presenting with normal or high pH because of associated metabolic alkalosis is commonly encountered and has received much attention. In such cases the respiratory acidosis may be inapparent and, therefore, may not be treated appropriately, with what may be serious consequences to the patient. A simple, readily available method is described to allow unmasking of the respiratory acidosis, and to separate patients with mixed respiratory acidosis-metabolic alkalosis from patients with pure metabolic alkalosis. This method is based on the observation that when inhaling 100 per cent oxygen for twelve minutes, overt respiratory acidosis often developed in patients with potential hypoventilation whatever their initial arterial gas values.

Original languageEnglish
Pages (from-to)513-519
Number of pages7
JournalAmerican Journal of Medicine
Volume45
Issue number4
DOIs
StatePublished - Oct 1968

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