Use of etanercept in treatment of pyoderma gangrenosum in a patient with autoimmune hepatitis

Gary Goldenberg, Joseph L. Jorizzo

Research output: Contribution to journalArticlepeer-review

40 Scopus citations

Abstract

A 30-year-old female with past medical history of autoimmune hepatitis was sent to our clinic for consultation and treatment of refractory pyoderma gangrenosum (PG) of bilateral lower extremities. At the time of presentation, she had failed treatment with prednisone, azathioprine and local wound care. Treatment options were limited by the patient's autoimmune hepatitis. This patient was treated with etanercept and a taper of oral prednisone, which resulted in a complete clinical cure of her PG. More studies are needed to evaluate the safety and efficacy of etanercept for PG in patients with liver disease.

Original languageEnglish
Pages (from-to)347-349
Number of pages3
JournalJournal of Dermatological Treatment
Volume16
Issue number5-6
DOIs
StatePublished - Dec 2005
Externally publishedYes

Keywords

  • Etanercept
  • Pyoderma gangrenosum

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