Urinary tritium excretion following intravenous 3h-norepinephrine administration in hypertensive rats

S. Gitlow, B. Wong, L. Dziedzic, S. Dziedzic

Research output: Contribution to journalArticlepeer-review

Abstract

Spontaneously hypertensive rats (SHR), salt-resistant (SRR), salt-sensitive (SSR), and Sprague-Dawley DOC-salt nephrectomized rats were tested by evaluation of tritiated norepinephrine uptake and blood pressure with diets containing various amounts of sodium. Only Sprague-Dawley rats who had been both nephrectomized and given DOC on a high salt diet (8% illustrated the elevated tritium excretion similar to that observed in human subjects with essential hypertension.

Original languageEnglish
Pages (from-to)169-182
Number of pages14
JournalClinical and Experimental Hypertension
Volume2
Issue number2
DOIs
StatePublished - 1980

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