@article{97e57b0f55704ae4887d017106a5f72a,
title = "Uptake of adenosine into cultured cerebral endothelium",
abstract = "Adenosine uptake by cultured cerebral endothelium is a carrier-mediated process. The Km value for adenosine uptake is 5.0 μM and the vmax is 1.15 nmol/min/mg cell protein. The uptake system is inhibited by the adenosine analog 2-chloroadenosine at low adenosine concentrations. The results prove the existence of a nucleoside transport system associated with cerebral capillary endothelium.",
keywords = "adenosine, cerebral endothelium, kinetics, uptake",
author = "Beck, {David W.} and Vinters, {Harry V.} and Hart, {Michael N.} and Henn, {Fritz A.} and Cancilla, {Pasquale A.}",
note = "Funding Information: The authors wish to thank Elizabeth Yoder and Cynthia TenEyck for their expert technical assistance. This work was supported by Arteriosclerosis Specialized Center of Research Grant for the National Heart, Lung and Blood Institute, National Institute of Health HL-14230, the R. Samuel Mc-Laughlin Foundation, and the Ontario Heart Foundation.",
year = "1983",
month = jul,
day = "18",
doi = "10.1016/0006-8993(83)91382-3",
language = "English",
volume = "271",
pages = "180--183",
journal = "Brain Research",
issn = "0006-8993",
publisher = "Elsevier B.V.",
number = "1",
}