Update of the guidelines for lupus anticoagulant detection

V. Pengo, A. Tripodi, G. Reber, J. H. Rand, T. L. Ortel, M. Galli, P. G. De groot

Research output: Contribution to journalComment/debate

952 Scopus citations


One of the conclusions of the subcommittee meeting on Lupus Anticoagulant/Phospholipid dependent antibodies, held in Geneva on 2007, was the need to update the guidelines on Lupus Anticoagulant (LA) detection. Particular emphasis was given to several aspects discussed in this official communication. A new paragraph is dedicated to the patient selection, and aims to minimize inappropriate requests for LA testing. Modalities for blood collection and processing are fully delineated and the choice of tests is limited to dRVVT and a sensitive aPTT. Calculation of cut-off values for each diagnostic step are clearly stated. A final paragraph reports the interpretation of the results in general and in particular situations.

Original languageEnglish
Pages (from-to)1737-1740
Number of pages4
JournalJournal of Thrombosis and Haemostasis
Issue number10
StatePublished - Oct 2009
Externally publishedYes


  • Anticoagulants
  • Antiphospholipid syndrome
  • Diagnosis
  • Lupus anticoagulant
  • Thrombosis


Dive into the research topics of 'Update of the guidelines for lupus anticoagulant detection'. Together they form a unique fingerprint.

Cite this