Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling

Sam Gandy; Derek M. Huffman

doi:10.1073/pnas.1901970116

Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling

Sam Gandy, Derek M. Huffman

Research output: Contribution to journal › Comment/debate

Original language	English
Pages (from-to)	5852-5854
Number of pages	3
Journal	Proceedings of the National Academy of Sciences of the United States of America
Volume	116
Issue number	13
DOIs	https://doi.org/10.1073/pnas.1901970116
State	Published - 2019

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10.1073/pnas.1901970116

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@article{28253fa6b7664392a050a1060e949c99,

title = "Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling",

author = "Sam Gandy and Huffman, {Derek M.}",

note = "Funding Information: S.G. is supported by NIH Grants R01 AG061894, U01 AG046170, R01AG058469, U01OH011314, and P50AG005138 and by Department of Veterans Affairs Rehabilitation Research and Development Service Awards 1I01RX000684 and 1I01RX002333. Additional support to S.G. was provided by the Rudin Family Foundation, the Alzheimer{\textquoteright}s Drug Discovery Foundation, the Werber Family Foundation, the Sara and Gideon Gartner Foundation, the Louis B. Mayer Foundation, the Jennifer and Scott Moskowitz Foundation, the Jane Martin and Stuart Katz Foundation, the Lady Va and Sir Deryck Maughan Foundation, the Georgianne and Dr. Reza Khatib Foundation, and the George B. Link Foundation. D.M.H. is supported by NIH Grants R01 AG057429, R21 AG055026, and P30 AG038072 and by the American Federation for Aging Research. Funding Information: S.G. is supported by NIH Grants R01 AG061894, U01 AG046170, R01AG058469, U01OH011314, and P50AG005138 and by Department of Veterans Affairs Rehabilitation Research and Development Service Awards 1I01RX000684 and 1I01RX002333. Additional support to S.G. was provided by the Rudin Family Foundation, the Alzheimer's Drug Discovery Foundation, the Werber Family Foundation, the Sara and Gideon Gartner Foundation, the Louis B. Mayer Foundation, the Jennifer and Scott Moskowitz Foundation, the Jane Martin and Stuart Katz Foundation, the Lady Va and Sir Deryck Maughan Foundation, the Georgianne and Dr. Reza Khatib Foundation, and the George B. Link Foundation. D.M.H. is supported by NIH Grants R01 AG057429, R21 AG055026, and P30 AG038072 and by the American Federation for Aging Research.",

year = "2019",

doi = "10.1073/pnas.1901970116",

language = "English",

volume = "116",

pages = "5852--5854",

journal = "Proceedings of the National Academy of Sciences of the United States of America",

issn = "0027-8424",

publisher = "National Academy of Sciences",

number = "13",

}

TY - JOUR

T1 - Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling

AU - Gandy, Sam

AU - Huffman, Derek M.

N1 - Funding Information: S.G. is supported by NIH Grants R01 AG061894, U01 AG046170, R01AG058469, U01OH011314, and P50AG005138 and by Department of Veterans Affairs Rehabilitation Research and Development Service Awards 1I01RX000684 and 1I01RX002333. Additional support to S.G. was provided by the Rudin Family Foundation, the Alzheimer’s Drug Discovery Foundation, the Werber Family Foundation, the Sara and Gideon Gartner Foundation, the Louis B. Mayer Foundation, the Jennifer and Scott Moskowitz Foundation, the Jane Martin and Stuart Katz Foundation, the Lady Va and Sir Deryck Maughan Foundation, the Georgianne and Dr. Reza Khatib Foundation, and the George B. Link Foundation. D.M.H. is supported by NIH Grants R01 AG057429, R21 AG055026, and P30 AG038072 and by the American Federation for Aging Research. Funding Information: S.G. is supported by NIH Grants R01 AG061894, U01 AG046170, R01AG058469, U01OH011314, and P50AG005138 and by Department of Veterans Affairs Rehabilitation Research and Development Service Awards 1I01RX000684 and 1I01RX002333. Additional support to S.G. was provided by the Rudin Family Foundation, the Alzheimer's Drug Discovery Foundation, the Werber Family Foundation, the Sara and Gideon Gartner Foundation, the Louis B. Mayer Foundation, the Jennifer and Scott Moskowitz Foundation, the Jane Martin and Stuart Katz Foundation, the Lady Va and Sir Deryck Maughan Foundation, the Georgianne and Dr. Reza Khatib Foundation, and the George B. Link Foundation. D.M.H. is supported by NIH Grants R01 AG057429, R21 AG055026, and P30 AG038072 and by the American Federation for Aging Research.

PY - 2019

Y1 - 2019

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U2 - 10.1073/pnas.1901970116

DO - 10.1073/pnas.1901970116

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AN - SCOPUS:85063953951

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JO - Proceedings of the National Academy of Sciences of the United States of America

JF - Proceedings of the National Academy of Sciences of the United States of America

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