Undetectable plasma HIV RNA load predicts success after hepatitis B vaccination in HIV-infected persons

Edgar Turner Overton, Somnuek Sungkanuparph, William G. Powderly, Warren Seyfried, Richard K. Groger, Judith A. Aberg

Research output: Contribution to journalArticlepeer-review

141 Scopus citations

Abstract

Human immunodeficiency virus (HIV)-infected patients respond poorly to hepatitis B vaccination. Records of 194 HIV-infected patients were reviewed for factors associated with successful hepatitis B vaccination. Thirty-four patients (17.5%) developed a protective antibody response. In a logistic regression model, only a plasma HIV RNA level of <400 copies/mL at the time of vaccination was associated with a protective antibody response (P = .003).

Original languageEnglish
Pages (from-to)1045-1048
Number of pages4
JournalClinical Infectious Diseases
Volume41
Issue number7
DOIs
StatePublished - 1 Oct 2005
Externally publishedYes

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