Underutilization of Coronary Artery Disease Testing Among Patients Hospitalized With New-Onset Heart Failure

Darshan Doshi, Ori Ben-Yehuda, Machaon Bonafede, Noam Josephy, Dimitri Karmpaliotis, Manish A. Parikh, Jeffrey W. Moses, Gregg W. Stone, Martin B. Leon, Allan Schwartz, Ajay J. Kirtane

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69 Scopus citations


Background Although ischemic coronary artery disease (CAD) is the most common etiology of heart failure (HF), the extent to which patients with new-onset HF actually undergo an ischemic work-up and/or revascularization is not well defined. Objectives This study sought to analyze the patterns of testing for ischemic CAD and revascularization in patients with new-onset HF. Methods This was a retrospective cohort study using Truven Health MarketScan Commercial and Medicare databases from 2010 to 2013. The occurrence of noninvasive and invasive ischemic CAD testing and revascularization procedures were examined among patients with new inpatient HF diagnoses during the index hospitalization and within 90 days of admission. Results Among 67,161 patients identified with new-onset HF during an inpatient hospitalization, only 17.5% underwent testing for ischemic CAD during the index hospitalization, increasing to 27.4% at 90 days. Among patients with new-onset HF, only 2.1% underwent revascularization during the index hospitalization for HF; by 90 days, the revascularization rate had increased to 4.3%. Of the tests performed for ischemic CAD, stress testing (nuclear stress testing or stress echocardiography) was performed in 7.9% of new-onset HF patients during the index hospitalization (14.6% within 90 days), whereas coronary angiography was performed in 11.1% of patients during the index hospitalization (16.5% within 90 days). In adjusted analyses, HF patients carrying a baseline diagnosis of CAD had greater odds of noninvasive ischemic testing (odds ratio: 1.25; 95% confidence interval: 1.17 to 1.33; p < 0.0001), as well as invasive ischemic testing (odds ratio: 1.93; 95% confidence interval: 1.83 to 2.05; p < 0.0001), at the index hospitalization than those without baseline CAD. Conclusions The majority of patients hospitalized for new-onset HF did not receive testing for ischemic CAD either during hospitalization or within 90 days, which suggests significant underutilization of ischemic CAD assessment in new-onset HF patients.

Original languageEnglish
Pages (from-to)450-458
Number of pages9
JournalJournal of the American College of Cardiology
Issue number5
StatePublished - 2 Aug 2016
Externally publishedYes


  • angiography
  • invasive
  • ischemic CAD
  • noninvasive
  • revascularization
  • stress testing


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