Skip to main navigation Skip to search Skip to main content

Understanding the murine cutaneous dendritic cell network to improve intradermal vaccination strategies

  • F. Ginhoux
  • , L. G. Ng
  • , M. Merad

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

17 Scopus citations

Abstract

Dendritic cells (DCs) form a heterogeneous group of antigen presenting cells that play different roles in tissue immunity. Recent studies have revealed the presence of distinct DC populations in murine skin, highlighting the complexity of the cutaneous DC network. In this review, we will define the major DC subsets that populate the different layers of the skin, focusing on their origin and the mechanisms controlling their homeostasis. We will also review recent evidence underlining the functional specialization of dermal DC subsets and its relevance in the design of novel vaccine approaches.

Original languageEnglish
Title of host publicationIntradermal Immunization
EditorsMarcel Teunissen
Pages1-24
Number of pages24
Edition1
DOIs
StatePublished - 2012

Publication series

NameCurrent Topics in Microbiology and Immunology
Number1
Volume351
ISSN (Print)0070-217X

Fingerprint

Dive into the research topics of 'Understanding the murine cutaneous dendritic cell network to improve intradermal vaccination strategies'. Together they form a unique fingerprint.

Cite this