Uncovering the global host cell requirements for influenza virus replication via RNAi screening

  • Silke Stertz
  • , Megan L. Shaw

Research output: Contribution to journalShort surveypeer-review

86 Scopus citations

Abstract

Influenza virus is reliant on numerous host cell functions during its replication cycle. RNA interference technology, applied on a genome-wide level, has identified human host factors that are necessary for efficient virus replication and provides new insight into how influenza virus interacts with its host at the molecular level.

Original languageEnglish
Pages (from-to)516-525
Number of pages10
JournalMicrobes and Infection
Volume13
Issue number5
DOIs
StatePublished - May 2011

Keywords

  • Influenza virus
  • RNA interference
  • Virus-host interactions

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