@article{8895e74e0b4d452ca16d60ff78c2baec,
title = "Uncloaking Breast Tumor Neoantigens with Radiation",
abstract = "Currently, immunotherapy is not effective for all cancer patients, partly due to an inability to mount sufficient tumor-specific T cell responses. Here, we highlight a recent study by Lhuillier et al. demonstrating that radiation potentiates neoantigen expression, eliciting CD4+ and CD8+ T cell responses and tumor growth control in mice.",
author = "Newman, {Jenna H.} and Nina Bhardwaj",
note = "Funding Information: This work was supported by the Training Program in Cancer Biology (T32CA078207-16A1) to J.H.N. N.B. is an extramural member of the Parker Institute for Cancer Immunotherapy. The authors declare that they have no competing interests related to this work. N.B. is an extramural member of the Parker Institute for Cancer Immunotherapy (PICI), receives research funds from Regeneron, Harbor Biomedical, and Dragonfly Therapeutics, and is on the advisory boards of Neon Therapeutics, Novartis, Avidea, Boehringer Ingelheim, ROME Therapeutics, Roswell Park Comprehensive Cancer Center, BreakBio, Carisma Therapeutics, CureVac, GenoTwin, BioNTech, Gilead, Tempest Therapeutics, and the Cancer Research Institute. Funding Information: This work was supported by the Training Program in Cancer Biology ( T32CA078207-16A1 ) to J.H.N. N.B. is an extramural member of the Parker Institute for Cancer Immunotherapy . Publisher Copyright: {\textcopyright} 2021 Elsevier Ltd",
year = "2021",
month = apr,
doi = "10.1016/j.it.2021.02.009",
language = "English",
volume = "42",
pages = "277--279",
journal = "Trends in Immunology",
issn = "1471-4906",
publisher = "Elsevier Ltd.",
number = "4",
}