Uncertainty in Medicine - Reply

Daniel J. Morgan; Lisa Pineles; Deborah Korenstein

doi:10.1001/jamainternmed.2021.3711

Uncertainty in Medicine - Reply

Daniel J. Morgan, Lisa Pineles, Deborah Korenstein

Research output: Contribution to journal › Letter › peer-review

Original language	English
Pages (from-to)	1417-1418
Number of pages	2
Journal	JAMA Internal Medicine
Volume	181
Issue number	10
DOIs	https://doi.org/10.1001/jamainternmed.2021.3711
State	Published - Oct 2021
Externally published	Yes

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10.1001/jamainternmed.2021.3711

Cite this

@article{e715debc65af43e78f36f46db06e34e9,

title = "Uncertainty in Medicine - Reply",

author = "Morgan, {Daniel J.} and Lisa Pineles and Deborah Korenstein",

note = "Funding Information: Administrative, technical, or material support: Joyce. Supervision: Trish, Van Nuys, Joyce. Conflict of Interest Disclosures: The Leonard D. Schaeffer Center for Health Policy & Economics is supported by a wide variety of public and private entities and donors, including health insurers and pharmaceutical manufacturers. More information on the Center's funding sources is available at https://healthpolicy. usc.edu/wp-content/uploads/2021/03/Schaeffer-Center-2020-Annual-Report. pdf. Dr Trish reported receiving grant support from Arnold Ventures and the Commonwealth Fund and personal fees from the Blue Cross Blue Shield Association, Cedars Sinai Health System, Cornerstone Research, Multiplan, Premera, and Varian Medical Systems, outside the submitted work. Disclaimer: The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of the Leonard D. Schaeffer Center for Health Policy & Economics. 1. Sood N, Shih T, Van Nuys K, Goldman DP. The flow of money through the pharmaceutical distribution system. Leonard D. Schaeffer Center for Health Policy & Economics. June 6, 2017. Accessed June 2, 2021. https://healthpolicy. usc.edu/research/flow-of-money-through-the-pharmaceutical-distribution-system/ 2. Yost D. Ohio{\textquoteright}s Medicaid Managed Care Pharmacy Services Auditor of State Report. Ohio Pharmacists Association. August 16, 2018. Accessed June 2, 2021. https://audits.ohioauditor.gov/Reports/AuditReports/2018/Medicaid_ Pharmacy_Services_2018_Franklin.pdf 3. Boards of Trustees, Federal Hospital Insurance and Federal Supplementary Medical Insurance Trust Funds. 2019 Annual Report of the Boards of Trustees of the Federal Hospital Insurance and Federal Supplementary Medical Insurance Trust Funds. Centers for Medicare & Medicaid Services. April 22, 2019. Accessed June 2, 2021. https://www.cms.gov/Research-Statistics-Data-and-Systems/ Statistics-Trends-and-Reports/ReportsTrustFunds/Downloads/TR2019.pdf 4. Cubanski J, Damico A, Neuman T. Medicare Part D in 2018: The Latest on Enrollment, Premiums, and Cost Sharing. Kaiser Family Foundation. May 17, 2018. Accessed June 2, 2021. https://www.kff.org/medicare/issue-brief/ medicare-part-d-in-2018-the-latest-on-enrollment-premiums-and-cost-sharing/ 5. Introduction to the Generic Drug Supply Chain and Key Considerations for Policymakers. Association for Accessible Medicines. October 13, 2017. Accessed June 2, 2021. https://accessiblemeds.org/sites/default/files/2017-10/AAM-Generic-Brand-Drug-Supply-Chain-Brief.pdf 6. 2019 Annual Report: Costco Wholesale. December 10, 2019. Accessed June 2, 2021. https://investor.costco.com/static-files/05c62fe6-6c09-4e16-8d8b-5e456e5a0f7e Funding Information: Conflict of Interest Disclosures: Dr Morgan reported receiving grants from the National Institutes of Health (NIH), the US Department of Veterans Affairs, the Agency for Healthcare Research and Quality, and the Centers for Disease Control and Prevention. Ms Pineles reported receiving grants from the NIH to the University of Maryland School of Medicine. Dr Korenstein reported receiving grants from the NIH and the National Cancer Institute to Memorial Sloan Kettering Cancer Center; and that her spouse serves on the scientific advisory board and as a consultant for Vedanta Biosciences and Opentrons, and serves as a consultant for Takeda. No other disclosures were reported. 1. Morgan DJ, Pineles L, Owczarzak J, et al. Accuracy of practitioner estimates of probability of diagnosis before and after testing. JAMA Intern Med. 2021;181 (6):747-755. doi:10.1001/jamainternmed.2021.0269 2. Morgan DJ, Scherer LD, Korenstein D. Improving physician communication about treatment decisions: reconsideration of “risks vs benefits”. JAMA.2020; 324(10):937-938. doi:10.1001/jama.2020.0354 3. Meyer AND, Singh H. The path to diagnostic excellence includes feedback to calibrate how clinicians think. JAMA. 2019;321(8):737-738. doi:10.1001/jama. 2019.0113 4. Morgan DJ, Leppin AL, Smith CD, Korenstein D. A practical framework for understanding and reducing medical overuse: conceptualizing overuse through the patient-clinician interaction. JHospMed. 2017;12(5):346-351. doi:10.12788/jhm.2738",

year = "2021",

month = oct,

doi = "10.1001/jamainternmed.2021.3711",

language = "English",

volume = "181",

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journal = "JAMA Internal Medicine",

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T1 - Uncertainty in Medicine - Reply

AU - Morgan, Daniel J.

AU - Pineles, Lisa

AU - Korenstein, Deborah

N1 - Funding Information: Administrative, technical, or material support: Joyce. Supervision: Trish, Van Nuys, Joyce. Conflict of Interest Disclosures: The Leonard D. Schaeffer Center for Health Policy & Economics is supported by a wide variety of public and private entities and donors, including health insurers and pharmaceutical manufacturers. More information on the Center's funding sources is available at https://healthpolicy. usc.edu/wp-content/uploads/2021/03/Schaeffer-Center-2020-Annual-Report. pdf. Dr Trish reported receiving grant support from Arnold Ventures and the Commonwealth Fund and personal fees from the Blue Cross Blue Shield Association, Cedars Sinai Health System, Cornerstone Research, Multiplan, Premera, and Varian Medical Systems, outside the submitted work. Disclaimer: The content of this article is solely the responsibility of the authors and does not necessarily represent the official views of the Leonard D. Schaeffer Center for Health Policy & Economics. 1. Sood N, Shih T, Van Nuys K, Goldman DP. The flow of money through the pharmaceutical distribution system. Leonard D. Schaeffer Center for Health Policy & Economics. June 6, 2017. Accessed June 2, 2021. https://healthpolicy. usc.edu/research/flow-of-money-through-the-pharmaceutical-distribution-system/ 2. Yost D. Ohio’s Medicaid Managed Care Pharmacy Services Auditor of State Report. Ohio Pharmacists Association. August 16, 2018. Accessed June 2, 2021. https://audits.ohioauditor.gov/Reports/AuditReports/2018/Medicaid_ Pharmacy_Services_2018_Franklin.pdf 3. Boards of Trustees, Federal Hospital Insurance and Federal Supplementary Medical Insurance Trust Funds. 2019 Annual Report of the Boards of Trustees of the Federal Hospital Insurance and Federal Supplementary Medical Insurance Trust Funds. Centers for Medicare & Medicaid Services. April 22, 2019. Accessed June 2, 2021. https://www.cms.gov/Research-Statistics-Data-and-Systems/ Statistics-Trends-and-Reports/ReportsTrustFunds/Downloads/TR2019.pdf 4. Cubanski J, Damico A, Neuman T. Medicare Part D in 2018: The Latest on Enrollment, Premiums, and Cost Sharing. Kaiser Family Foundation. May 17, 2018. Accessed June 2, 2021. https://www.kff.org/medicare/issue-brief/ medicare-part-d-in-2018-the-latest-on-enrollment-premiums-and-cost-sharing/ 5. Introduction to the Generic Drug Supply Chain and Key Considerations for Policymakers. Association for Accessible Medicines. October 13, 2017. Accessed June 2, 2021. https://accessiblemeds.org/sites/default/files/2017-10/AAM-Generic-Brand-Drug-Supply-Chain-Brief.pdf 6. 2019 Annual Report: Costco Wholesale. December 10, 2019. Accessed June 2, 2021. https://investor.costco.com/static-files/05c62fe6-6c09-4e16-8d8b-5e456e5a0f7e Funding Information: Conflict of Interest Disclosures: Dr Morgan reported receiving grants from the National Institutes of Health (NIH), the US Department of Veterans Affairs, the Agency for Healthcare Research and Quality, and the Centers for Disease Control and Prevention. Ms Pineles reported receiving grants from the NIH to the University of Maryland School of Medicine. Dr Korenstein reported receiving grants from the NIH and the National Cancer Institute to Memorial Sloan Kettering Cancer Center; and that her spouse serves on the scientific advisory board and as a consultant for Vedanta Biosciences and Opentrons, and serves as a consultant for Takeda. No other disclosures were reported. 1. Morgan DJ, Pineles L, Owczarzak J, et al. Accuracy of practitioner estimates of probability of diagnosis before and after testing. JAMA Intern Med. 2021;181 (6):747-755. doi:10.1001/jamainternmed.2021.0269 2. Morgan DJ, Scherer LD, Korenstein D. Improving physician communication about treatment decisions: reconsideration of “risks vs benefits”. JAMA.2020; 324(10):937-938. doi:10.1001/jama.2020.0354 3. Meyer AND, Singh H. The path to diagnostic excellence includes feedback to calibrate how clinicians think. JAMA. 2019;321(8):737-738. doi:10.1001/jama. 2019.0113 4. Morgan DJ, Leppin AL, Smith CD, Korenstein D. A practical framework for understanding and reducing medical overuse: conceptualizing overuse through the patient-clinician interaction. JHospMed. 2017;12(5):346-351. doi:10.12788/jhm.2738

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