Ultrasonic biophysical measurements in the normal human fetus for optimal design of the monolithic fetal pacemaker

Evgueni Fayn, Howard A. Chou, Dae Gyun Park, Daniel H. Zavitz, Bettina F. Cuneo, Vicki L. Mahan, Mehmet Guleçyuz, Letitia Curran, David Lipson, Edmond W. Quillen, Boris M. Petrikovsky, Marc Ovadia

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Ultrasound measurements, including xiphoid-to-pericardial distance and deployment angle, were made on human fetuses as a function of gestational age for the purpose of assessing the likelihood of 3 failure modes of a monolithic fetal pacemaker, including primary positioning failure due to device length and secondary dislodgement failure due to somatic growth. The small variation of the measurements over the gestational age range relevant to device implantation for the major indications of the device (for complete heart block complicated by hydrops and for bradycardia risk after fetal surgery or intrauterine intervention) predicts a small likelihood of these failure modes.

Original languageEnglish
Pages (from-to)1267-1270
Number of pages4
JournalAmerican Journal of Cardiology
Volume95
Issue number10
DOIs
StatePublished - 15 May 2005

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