Ulcerative colitis

Adam F. Steinlauf; Daniel H. Present

doi:10.1002/9781118932759.ch36

Ulcerative colitis

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Ulcerative colitis is a chronic inflammatory condition of the colon. Typical symptoms include diarrhea with blood associated with urgency, tenesmus, frequent stools, and abdominal pain and cramps. Evaluation should begin with blood tests including complete blood count, chemistries, erythrocyte sedimentation rate, C-reactive protein, and/or fecal calprotectin. Stool studies should also be sent to exclude infections as a cause of the presentation. Lastly, endoscopic assessment with flexible sigmoidoscopy or colonoscopy with biopsies is necessary to confirm the diagnosis while providing information on extent and severity of disease. Treatment is aimed initially at achieving remission followed by maintenance of remission. Medications include anti-inflammatory agents such as mesalamine, corticosteroids, thiopurine immunomodulators, and biologic agents. Colectomy is curative.

Original language	English
Title of host publication	Gastroenterology
Publisher	wiley
Pages	379-389
Number of pages	11
ISBN (Electronic)	9781118932759
ISBN (Print)	9781118519967
DOIs	https://doi.org/10.1002/9781118932759.ch36
State	Published - 1 Jan 2014
Externally published	Yes

Keywords

Diarrhea
Inflammatory bowel disease
Rectal bleeding
Ulcerative colitis

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10.1002/9781118932759.ch36

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AU - Present, Daniel H.

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AB - Ulcerative colitis is a chronic inflammatory condition of the colon. Typical symptoms include diarrhea with blood associated with urgency, tenesmus, frequent stools, and abdominal pain and cramps. Evaluation should begin with blood tests including complete blood count, chemistries, erythrocyte sedimentation rate, C-reactive protein, and/or fecal calprotectin. Stool studies should also be sent to exclude infections as a cause of the presentation. Lastly, endoscopic assessment with flexible sigmoidoscopy or colonoscopy with biopsies is necessary to confirm the diagnosis while providing information on extent and severity of disease. Treatment is aimed initially at achieving remission followed by maintenance of remission. Medications include anti-inflammatory agents such as mesalamine, corticosteroids, thiopurine immunomodulators, and biologic agents. Colectomy is curative.

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KW - Rectal bleeding

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ER -

Ulcerative colitis

Abstract

Keywords

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