Typhlitis in a patient with acute lymphoblastic leukemia prior to the administration of chemotherapy

Augusto F.G. Paulino, Robert Kenney, Edwin N. Forman, L. Jeffrey Medeiros

Research output: Contribution to journalArticlepeer-review

30 Scopus citations

Abstract

Patients and Methods A 3-year-old girl with acute lymphoblastic leukemia developed typhlitis immediately after diagnosis and before the institution of chemotherapy.: Purpose Typhlitis is a necrotizing colitis that develops in immunodeficient patients with severe neutropenia. Most patients are leukemic children who are receiving or have received chemotherapy. Typhlitis in the absence of chemotherapy is rare. We report a fatal case of typhlitis in an untreated leukemic patient.: Results This case emphasizes the multifactorial pathogenesis of typhlitis, which may occur in the absence of chemotherapy.: Conclusions Typhlitis should always be considered as a potential cause of acute sepsis and abdominal pain in a leukemic patient.

Original languageEnglish
Pages (from-to)348-351
Number of pages4
JournalAmerican Journal of Pediatric Hematology/Oncology
Volume16
Issue number4
StatePublished - Nov 1994
Externally publishedYes

Keywords

  • Acute lymphoblastic leukemia
  • Chemotherapy
  • Neutropenia
  • Typhlitis

Fingerprint

Dive into the research topics of 'Typhlitis in a patient with acute lymphoblastic leukemia prior to the administration of chemotherapy'. Together they form a unique fingerprint.

Cite this